Paroxetine Mesylate

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Brand Names
Brisdelle, Paxil, Paxil CR, Pexeva

Paroxetine mesylate Information

Paroxetine is a antidepressant in a group of medications called selective serotonin reuptake inhibitors . Paroxetine affects chemicals in the brain which might be unbalanced in individuals with nervousness depression, or other ailments.Paroxetine is used to treat depression, obsessive-compulsive disorder, stress disorders, post-traumatic stress disorder , and premenstrual dysphoric disorder .Even the Brisdelle brand of paroxetine is used to treat.

For handling any other problems, Brisdelle isn’t.Paroxetine may also be used for purposes not listed in this medication guide.

Used for treatment: Generalized Anxiety Disorder, Vasomotor Symptoms

Paroxetine is a potent and highly selective inhibitor of neuronal serotonin reuptake. Paroxetine probably inhibits the reuptake of serotonin at the adrenal gland, enhances serotonergic neurotransmission by reducing turnover of their neurotransmitter, therefore it prolongs its activity at synaptic receptor sites and potentiates 5-HT from the CNS; paroxetine is more potent than both and in its ability to inhibit 5-HT reuptake. Compared to the tricyclic antidepressants, SSRIs have dramatically diminished binding to histamine, acetylcholine, and norepinephrine receptors. The mechanism of action for the treatment of vasomotor symptoms is unknown.

How to use paroxetine mesylate

Follow all directions on your prescription label. Your dose may occasionally change. Don’t take this medicine in smaller or larger quantities or for longer than advised. Don’t crush, chew, or break an extended-release pillcomputer. Swallow it whole. Shake the suspension until a dose is measured by you. Measure liquid medication with the syringe supplied, or with a special dose-measuring spoon or medicine cup.

If you do not have a dose-measuring device, ask your pharmacist for one. It might take up to 4 weeks before your symptoms change. Continue using the medicine as directed and inform your physician if your symptoms don’t improve. Don’t quit using paroxetine unexpectedly, or you could have withdrawal symptoms. Ask your doctor how to safely quit using paroxetine. About tapering your dose, follow your physician’s instructions. Store at room temperature away from heat, moisture, and light.

Side Effects

  • shaking
  • not feeling hungry
  • yawning
  • feeling anxious or trouble sleeping
  • headache
  • weakness
  • dry mouth
  • constipation
  • sweating
  • dizziness
  • infection
  • nausea
  • sexual problems
  • sleepiness

Interactions

All SSRIs, including paroxetine, shouldn’t be taken for instance, isocarboxazid, phenelzine, tranylcypromine, , and procarbazine or drugs that inhibit monoamine oxidase such as linezolid and intravenous methylene blue. Such combinations may lead to hyperactivity, high blood pressure, tremor, confusion, coma, and death.

Similar reactions happen when paroxetine is blended with other medications for instance, tryptophan, St. John’s wort, meperidine , tramadol that increase dopamine within the brain. Paroxetine can increase the impact of the blood thinner, , leading to excessive bleeding. Therefore, warfarin therapy should be monitored in patients that are currently taking paroxetine.

Combining SSRIs like paroxetine with aspirin, nonsteroidal anti-inflammatory drugs or other medications that affect bleeding might increase the probability of upper gastrointestinal bleeding. and phenobarbital may decrease the amount of paroxetine in the human body and reduce its effectiveness.

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