Atorvastatin

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40mg, 20mg, 10mg, 5mg
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Brand Names
Caduet, Lipitor, Liptruzet

Atorvastatin Information

Atorvastatin is in a group of drugs known as HMG CoA reductase inhibitors, or “statins.” Atorvastatin reduces amounts of “bad” cholesterol And triglycerides from the blood, while raising amounts of “good” cholesterol . Atorvastatin can be used to treat hypertension, and also to decrease the chance of heart attack, stroke, or other cardiovascular problems in individuals with coronary heart disease, type 2 diabetes, along with risk factors.Atorvastatin can be used in adults and kids who are at least 10 years old.Atorvastatin may also be used for purposes not listed in this medication guide.

Used for treatment: Cardiovascular Diseases, Cardiovascular disorder prophylaxis, Dysbetalipoproteinemia, Familial hyperlipidemia, Heterozygous Familial Hypercholesterolemia, Homozygous Familial Hypercholesterolemia, Hypercholesterolaemia, Hypertriglyceridemias, Mixed hypercholesterolemia

Atorvastatin selectively and competitively inhibits the hepatic enzyme HMG-CoA reductase. As HMG-CoA reductase is responsible for converting HMG-CoA into mevalonate in the cholesterol biosynthesis pathway, this ends in a subsequent decrease in hepatic cholesterol levels. Decreased hepatic cholesterol levels arouses upregulation of hepatic LDL-C receptors that increases hepatic uptake of both LDL-C and reduces serum LDL-C concentrations.

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How to use atorvastatin

Follow all instructions. Your physician may change your dose. Don’t use this medication in larger or smaller quantities or for longer than suggested. Take the medicine. Before taking it, do not break an atorvastatin tablet.

It might take as many as 2 months before your cholesterol levels grow, and you may need frequent blood tests.

You may not notice any change in your symptoms, but bear using the medication. Your blood work will help your doctor determine to cure you with atorvastatin. Atorvastatin is just part of an entire treatment system which may incorporate exercise, diet, and weight control. Follow your physician’s instructions very closely.

Store at room temperature away from heat, moisture, and light.

Side Effects

  • Muscle problems. Atorvastatin can cause serious muscle problems that can lead to kidney problems, including kidney failure. You have a higher chance for muscle problems if you are taking certain other medicines with atorvastatin.
  • you feel more tired than usual
  • your skin and whites of your eyes get yellow.
  • hives
  • muscle problems like weakness, tenderness, or pain that happen without a good reason, especially if you also have a fever or feel more tired than usual.
  • passing brown or dark-colored urine.
  • neck pain
  • joint swelling
  • yellowing of your skin or the whites of your eyes
  • dark amber colored urine
  • nausea and vomiting.
  • allergic skin reactions.
  • allergic reactions including swelling of the face, lips, tongue, and/or throat that may cause difficulty in breathing or swallowing which may require treatment right away.
  • Liver problems. Your doctor should do blood tests to check your liver before you start taking atorvastatin and if you have symptoms of liver problems while you take atorvastatin. Call your doctor right away if you have the following symptoms of liver problems:
    • feel tired or weak
    • general feeling of discomfort (malaise)
    • upper belly pain
    • loss of appetite
    • fever
    • stomach pain.

    Interactions

    Elimination of Lipitor increase the risk of muscle fatigue from Lipitor and could increase levels of Lipitor. Lipitor shouldn’t be combined. Examples of such medications includes: erythromycin, ketoconazole, itraconazole, clarithromycin, telithromycin, cyclosporine, nefazodone, and HIV protease inhibitors such as ritonavir and indinavir. Massive amounts of fruit juice can also increase blood levels of Lipitor and should not be taken.

    When combined with Lipitor the risk of muscle fatigue also may increase. Amiodarone verapamil cyclosporine niacin gemfibrozil fenofibrate Lipitor raises the impact of warfarin as well as the concentration in blood of digoxin. Patients taking warfarin or digoxin and Lipitor ought to be monitored. Cholestyramine decreases the absorption of Lipitor.

    Lipitor should be given at least 2 hours before and at least four hours after cholestyramine. Breakdown of Lipitor increases. To decrease the likelihood of this interaction both drugs should be provided in precisely the exact same time. Lipitor should not be given following rifampin.

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