Azathioprine

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Brand Names
Azasan, Imuran

Azathioprine Information

Azathioprine lowers your body’s immune system. The immune system helps your body fight diseases. The immune system may also combat or “reject” a transplanted organ such as a kidney or liver. This can be mainly because the system heals the new organ as an invader.Azathioprine is used to prevent your body. It is utilised in the treatment of symptoms of arthritis.Azathioprine may also be used for purposes not listed in this medication guide.

Used for treatment: Crohn's Disease, Uveitis

Azathioprine antagonizes purine metabolism and might inhibit synthesis of DNA, RNA, and proteins. It might also interfere with cellular metabolism and inhibit mitosis. Its mechanism of action is more likely due to incorporation of thiopurine analogues to the DNA structure, resulting in chain termination and cytotoxicity.

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How to use azathioprine

Your doctor may do blood tests to make sure you do not have conditions that would prevent you from with azathioprine. Follow all instructions on your prescription label. Your physician may sometimes change your dose. Do not take this medication in smaller or bigger quantities or for longer than recommended. Take azathioprine with meals to lessen stomach upset. You may not be able to continue carrying arthritis medications. Follow your physician’s dosing directions carefully.

Azathioprine help your blood to clot and can reduce. This can make it more easy for you to bleed from an accident or becoming sick from being around others who are ill. Your blood will need to get tested often. It may take up to 2 months before your symptoms change. Keep using the medicine and tell your physician if your symptoms do not improve. Should you need surgery, tell the physician ahead of time which you’re currently using azathioprine.

You might need to stop using the medicine for a brief moment. Store at room temperature away from moisture, heat, and light.

Side Effects

  • hair loss
  • diarrhea
  • rash
  • fever
  • muscle aches
  • hair loss
  • vomiting
  • nausea

Interactions

Allopurinol that is used for preventing gout and treating blood levels of uric acid increases amounts. It is important to decrease the dose of azathioprine by roughly 1/3 to 1/4 in patients. The use of enzyme inhibitors to control blood pressure in patients has been reported to cause leukopenia and nausea. Azathioprine reduces blood circulation of the blood thinner and thus can reduce the blood thinning effect of warfarin.

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