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Chloramphenicol sodium succinate Information
Chloramphenicol is lipid-soluble, allowing it to diffuse through the bacterial cell membrane. It then reversibly binds to the L16 protein of the 50S subunit of bacterial ribosomes, where transport of amino acids into growing peptide chains is prevented (possibly by suppression of peptidyl transferase activity), thus inhibiting peptide bond formation and subsequent protein synthesis.
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