Anabolism is the biosynthesis of metabolic products (proteins, fats, carbohydrates), in contrast to catabolism – another component of metabolism, which means the breakdown (degradation) of the same products. Both processes in the body are realized by enzymatic pathways (in the vast majority of cases).
Certain steroid and non-steroidal compounds have anabolic effect.
Of the steroid substances, preparations of male sex hormones – androgens – have anabolic activity. However, their use as therapeutic anabolic agents is hampered by androgenic properties. In this regard, compounds were synthesized that are structurally similar to androgens (steroids), but have predominantly anabolic activity. They are called anabolic steroids.
The most characteristic property of substances in this group is their ability to stimulate protein synthesis in the body and cause a decrease in nitrogen excretion (positive nitrogen balance). The release of potassium, sulfur and phosphorus necessary for the synthesis of proteins is also reduced. Anabolic medications help fix calcium in the bones. Clinically, the effect of steroidal anabolic steroids is manifested in an increase in appetite, improved performance, the general condition of patients, and an increase in body weight. Drugs in this group help accelerate bone calcification (with osteoporosis). To achieve a pronounced effect, simultaneously with anabolic drugs, patients should receive adequate amounts of proteins, fats, carbohydrates, vitamins and minerals with food. Different drugs belonging to the group of steroid anabolic steroids have different strength and duration of anabolic effect and also differ in residual androgenic activity.
Below is a list of anabolic steroids:
- Orotic acid
- Dioxomethyltetrahydropyrimidine (Dioxomethyltetrahydropyrimidinum)
- Silabolin (Silabolinum)