Antineoplastic antibiotics – a pharmacological group that combines anticancer antibiotic drugs with antitumor action.
The first antitumor antibiotic, dactinomycin, was obtained in 1963. Subsequently, the screening of microbial waste products led to the discovery of a number of effective chemotherapeutic anticancer drugs that are products of different types of soil fungi or their synthetic derivatives.
Anthracycline drugs are among the most effective antineoplastic agents. These antibiotics are bleomycin, which is a phleomycin, dactinomycin, which is actinomycin, and mitomycin, a kind of antibiotic with an alkylating mechanism of action. Anthracycline antibiotics have an immuno-depressive and antibacterial effect, however, they are not used as antimicrobial agents. They are used for many malignant neoplasms (various hematological cancers, soft tissue sarcomas, carcinomas, etc.).
Antineoplastic antibiotics are used alone or more often in combination with other drugs and radiation therapy.
Below is a list of anticancer antibiotics: