Cholinomimetic

Drugs belonging to this group interact with n-cholinergic receptors located in the autonomic ganglia (sympathetic and parasympathetic), and the so-called. analogs of ganglionic tissue (carotid sinus and adrenal medulla). In addition, they have the ability to excite n-cholinergic receptors located in the central nervous system. The main effects of drugs of this group are reflex…

Read More N-cholinomimetics

The drugs of this group reproduce the effects of the mediator of the parasympathetic nervous system – acetylcholine, due to its interaction with m-cholinergic receptors. m-Cholinergic receptors are localized in all organs receiving parasympathetic innervation, at the end of the postganglionic parasympathetic fibers. m-Cholinergic receptors are heterogeneous. Interaction with the m1-cholinergic receptors of the central…

Read More M-cholinomimetics

Acetylcholine chloride, carbachol – the so-called direct cholinomimetics have a stimulating effect on cholinergic transmission. They directly interact with m- and n-cholinergic receptors. However, anticholinesterase agents (physostigmine, galantamine, neostigmine methyl sulfate, pyridostigmine bromide, aminostigmine, rivastigmine, ipidacrine, etc.) are more often used for this purpose. They inhibit cholinesterase – an enzyme that destroys endogenous acetylcholine, cause…

Read More M-cholinomimetics, n-cholinomimetics, including anticholinesterase

The section of cholinomimetic drugs includes drugs that enhance transmission in cholinergic synapses, usually peripheral. They are used to treat pathological conditions associated with impairment (weakening) of cholinergic impulses.

Read More Cholinomimetic