Corticosteroids

The main endogenous mineralocorticoids are aldosterone and deoxycorticosterone. These hormones actively affect the exchange of electrolytes and water, and relatively little – on carbohydrate and protein metabolism. Earlier in clinical practice, deoxycortone preparations – deoxycorticosterone acetate (DOXA) and deoxycorticosterone trimethyl acetate – were widely used. They were used for adrenal dysfunction (hypocorticism), especially in Addison’s…

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This pharmacological group includes corticosteroids such as glucocorticosteroids in combinations. Below is a list of glucocorticosteroids in combinations: Betamethasone + Gentamicin Betamethasone + Gentamicin + Clotrimazole Betamethasone + Salicylic acid Betamethasone + Interferon alpha-2b Betamethasone + Chlorhexidine Betamethasone + Gentamicin + Miconazole Hydrocortisone + Lidocaine Hydrocortisone + Oxytetracycline Betamethasone + Calcipotriol Gentamicin + Dexamethasone Dexamethasone…

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Glucocorticoids are steroid hormones synthesized by the adrenal cortex. Natural glucocorticoids and their synthetic analogues are used in medicine for adrenal insufficiency. In addition, in some diseases, anti-inflammatory, immunosuppressive, antiallergic, anti-shock and other properties of these drugs are used. The beginning of the use of glucocorticoids as medicines (drugs) dates back to the 40s. XX…

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The adrenal cortex of mammals and humans produces many steroid hormones called corticosteroids. They are derivatives of pregnane and are chemically divided into 11-deoxyteroids, 11-oxysteroids and 11,17-oxysteroids. The first group includes deoxycorticosterone. The 11,17-oxysteroid group includes cortisone, cortisol (hydrocortisone) and a number of their derivatives. Cortisone, hydrocortisone, deoxycorticosterone are endogenous substances produced in the body.…

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