Intermediates

The generation of imidazoline receptors is represented by two subtypes: Ione-imidazoline and I2-imidazoline receptors. Central Ione-imidazoline receptors are located in the rostral ventrolateral part of the medulla oblongata, which is responsible for tonic and reflex control over the sympathetic nervous system. Peripheral Ione– and I2-imidazoline receptors are found on the membranes of epithelial cells of…

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Intermediate-type drugs include substances that specifically interact with certain systems of mediators / modulators. Basically, they are agonists or antagonists of the corresponding receptors. The action of some of them is mediated through endogenous ligands by altering their metabolism, release, capture and deposition. Among the intermediates, drugs are distinguished with a predominant effect on dopaminergic,…

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