Mineralocorticosteroids

The main endogenous mineralocorticoids are aldosterone and deoxycorticosterone. These hormones actively affect the exchange of electrolytes and water, and relatively little – on carbohydrate and protein metabolism. Earlier in clinical practice, deoxycortone preparations – deoxycorticosterone acetate (DOXA) and deoxycorticosterone trimethyl acetate – were widely used. They were used for adrenal dysfunction (hypocorticism), especially in Addison’s…

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