Vegetotropic

Drugs belonging to this group interact with n-cholinergic receptors located in the autonomic ganglia (sympathetic and parasympathetic), and the so-called. analogs of ganglionic tissue (carotid sinus and adrenal medulla). In addition, they have the ability to excite n-cholinergic receptors located in the central nervous system. The main effects of drugs of this group are reflex…

Read More N-cholinomimetics

The drugs of this group reproduce the effects of the mediator of the parasympathetic nervous system – acetylcholine, due to its interaction with m-cholinergic receptors. m-Cholinergic receptors are localized in all organs receiving parasympathetic innervation, at the end of the postganglionic parasympathetic fibers. m-Cholinergic receptors are heterogeneous. Interaction with the m1-cholinergic receptors of the central…

Read More M-cholinomimetics

Acetylcholine chloride, carbachol – the so-called direct cholinomimetics have a stimulating effect on cholinergic transmission. They directly interact with m- and n-cholinergic receptors. However, anticholinesterase agents (physostigmine, galantamine, neostigmine methyl sulfate, pyridostigmine bromide, aminostigmine, rivastigmine, ipidacrine, etc.) are more often used for this purpose. They inhibit cholinesterase – an enzyme that destroys endogenous acetylcholine, cause…

Read More M-cholinomimetics, n-cholinomimetics, including anticholinesterase

The section of cholinomimetic drugs includes drugs that enhance transmission in cholinergic synapses, usually peripheral. They are used to treat pathological conditions associated with impairment (weakening) of cholinergic impulses.

Read More Cholinomimetic

This pharmacological group includes such anticholinergics as n-anticholinergics (muscle relaxants). Below is a list of n-anticholinergics (muscle relaxants): Pipecuronium bromide Atracuria besilat Suxamethonii iodidum (Suxamethonii iodidum) Rocuronium bromide Suxamethonium chloride Mivacuria chloride Tolperisone Cisatracuria besilat Tercuronium (Tercuronium) Tubocurarine chloride

Read More N-anticholinergics muscle relaxants

Nicotine-sensitive cholinergic receptors (n-cholinergic receptors) are mainly localized on the postsynaptic membranes in the synapses of skeletal muscles, autonomic nerve nodes (ganglia), adrenal medulla and carotid sinus zones (evolutionarily both of the latter formations are ganglia), some interneuronal contacts. n-anticholinergics have the ability to screen receptors and prevent their excitation by acetylcholine. Thus, the transmission…

Read More N-anticholinergics ganglion blockers

This pharmacological group includes such anticholinergics as m-anticholinergics in combinations. Below is a list of m-anticholinergics in combinations: Belladonna leaf extract + Tribromphenolate bismuth and Bismuth oxide complex + Zinc sulfate (Extractum foliorum Belladonnae + Bismuthi tribromphenolas cum Bismuthi oxydo complexus (Xeroformium) + Zinci sulfas) Belladonna leaf extract + Sodium bicarbonate (Extractum foliorum Belladonnae +…

Read More M-anticholinergics in combinations

M-anticholinergics include substances that block m-cholinergic receptors in the region of the endings of parasympathetic nerve fibers, resulting in dilated pupils, accommodation paralysis, tachycardia, improved AV conduction, decreased tone of the bronchi, bladder, weakening of intestinal motility, decreased secretion of glands (bronchial and digestive). Some alkaloids (atropine, scopolamine), a number of semi-synthetic and synthetic compounds…

Read More M-anticholinergics