Esomeprazole Sodium

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Brand Names
Nexium

Esomeprazole sodium Information

Esomeprazole is a proton pump inhibitor that decreases the amount of acid produced in your stomach.Esomeprazole is used to treat symptoms of gastroesophageal reflux disease And other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Esomeprazole is utilised to encourage healing of erosive esophagitis . Esomeprazole may also be given to prevent gastric ulcer brought on by infection with helicobacter pylori , or from the use of nonsteroidal anti-inflammatory drugs .Esomeprazole isn’t for immediate relief of asthma symptoms.Esomeprazole may also be used for purposes.

Used for treatment: Erosive Esophagitis(EE), GERD, Gastric ulcer caused by NSAID, Heartburn, Helicobacter Pylori Infections, Stress Ulcers, Zollinger-Ellison Syndrome, Maintenance of healing Erosive esophagitis, Postendoscopy Bleeding

Esomeprazole is a proton pump inhibitor that inhibits gastric acid secretion by specific inhibition of the H /K -ATPase in the gastric parietal cell. By acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity.

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How to use esomeprazole sodium

Use as directed on the label, or as prescribed by your doctor. Don’t use in bigger or smaller quantities or for longer than suggested. This medication is often given for 4 weeks to 8 weeks only. In case you need extra healing time, your doctor may suggest a course of treatment. Take each dose with a full glass of plain water. Esomeprazole ought to be taken a minumum of one hour before a meal.

You might open the esomeprazole capsule and sprinkle the medication to a spoonful of applesauce or pudding, to make swallowing easier. Swallow right away without chewing. Don’t store the mixture for later use. Esomeprazole could be given through a feeding tube. Open the capsule and sprinkle the medicine. Mix at 50 milliliters of water. Place the plunger into the syringe and shake the mixture well. Make sure that there aren’t any medicine granules.

Attach the syringe and push on down the plunger into empty the syringe to the tube. Then flush the tube with water to wash down off the contents. Take this medication for the total length of time. You could develop an vitamin B-12 deficiency, in the event you use esomeprazole for more than 3 years. Speak with your doctor if you develop it, about how to handle this illness.

Call your doctor if your symptoms don’t improve or if they get worse while you are taking this medication. Esomeprazole can cause results with certain evaluations, and you might want to stop using the medicine for a short period. Store at room temperature away from heat and moisture.

Side Effects

  • abdominal pain
  • nausea
  • gas
  • dry mouth
  • headache
  • constipation
  • drowsiness
  • diarrhea

Interactions

By decreasing the elimination of diazepam the concentration in blood flow of diazepam possibly cans raise. Esomeprazole might have fewer drug interactions than omeprazole. The absorption of certain drugs may be affected by stomach acidity. Esomeprazole and other PPIs increase the absorption and concentration in blood of digoxin and that reduce stomach acid also reduce the absorption and concentration.

This can lead to reduced effectiveness of ketoconazole or raised digoxin toxicity. Through unknown mechanisms, esomeprazole may increase blood levels of saquinavir and decrease blood levels of nelfinavir and atazanavir , Hence, nelfinavir or atazanavir shouldn’t be administered with esomeprazole, and physicians should consider reducing the dose of saquinavir to be able to prevent unwanted effects from saquinavir. Clopidogrel is converted into its active form by enzymes from the liver.

Esomeprazole reduces the activity of these enzymes and possibly can reduce the activity of clopidogrel. Esomeprazole shouldn’t be used with clopidogrel. Esomeprazole increases the concentration of cilostazol and its metabolites. The dose of cilostazol ought to be decreased from 100 mg twice per day to 50 mg daily when given with esomeprazole. Esomeprazole may increase blood levels of methotrexate and tacrolimus.