Ezetimibe

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Brand Names
Zetia

Ezetimibe Information

Ezetimibe reduces the amount of cholesterol absorbed in the human body.Ezetimibe is used as a treatment for high cholesterol. Ezetimibe can be given with other cholesterol-lowering drugs.Ezetimibe may also be used for purposes.

Used for treatment: Familial hyperlipidemia, Homozygous Familial Hypercholesterolemia, Homozygous Sitosterolemia, Mixed hypercholesterolemia

Ezetimibe localizes and appears to act at the brush border of the small intestine and inhibits the absorption of cholesterol. This also contributes to a drop in the delivery of intestinal cholesterol to the liver.

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How to use ezetimibe

Follow all instructions. Do not take this medication in larger or smaller amounts or for longer than advised. Ezetimibe is usually taken once daily. Take the medicine. You may take ezetimibe without or with food. Ezetimibe could be taken in precisely the identical time together with fenofibrate, or with a statin medication such as atorvastatin. Some cholesterol medicines should not be taken at precisely the exact same moment.

  • In the event you also take cholestyramine, colestipol, or colesevelam: Wait at least 4 hours after taking one of these medicines before you take ezetimibe.

    Prior to taking some of the other medications you may take ezetimibe 2 hours.

  • You shouldn’t take ezetimibe using gemfibrozil.

You might need regular blood tests to assess your liver work should you choose ezetimibe with a statin medicine. Before your cholesterol levels enhance, it may take up to two months. Keep using your medication as directed. You’ll need blood tests to measure your cholesterol levels.

Ezetimibe is only part of an entire application of treatment which includes exercise, diet, and weight management.

Side Effects

  • If you experience unexplained muscle pain, tenderness, or weakness while taking ezetimibe, contact your doctor immediately.
  • depression
  • joint pain
  • stomach pain
  • alterations in some laboratory blood tests
  • liver problems
  • Patients have experienced severe muscle problems while taking ezetimibe, usually when ezetimibe was added to a statin drug.
  • inflammation of the pancreas
  • allergic reactions (which may require treatment right away) including swelling of the face, lips, tongue, and/or throat that may cause difficulty in breathing or swallowing,
  • You need to do this promptly, because on rare occasions, these muscle problems can be serious, with muscle breakdown resulting in kidney damage.
  • muscle aches
  • gallstones
  • nausea
  • In clinical studies patients reported few side effects while taking ezetimibe. These included diarrhea, joint pains, upper airway infection, and feeling tired.
  • dizziness
  • inflammation of the gallbladder
  • headache
  • raised red rash, sometimes with target-shaped lesions
  • rash, and hives
  • tingling sensation

Interactions

Cholestyramine, colestipol and colesevelam, bile acid-binding drugs that may be used to deal with elevated levels of cholesterol, bind to ezetimibe and reduce its absorption in the intestine by about 50%. Consequently, ezetimibe should be taken after administration of those medications. The levels of ezetimibe increase while ezetimibe increases levels of cyclosporine. Unwanted side effects of either drug may increase.

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