Indinavir

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Brand Names
Crixivan

Indinavir Information

Indinavir is a protease Inhibitor antifungal medication that prevents human immunodeficiency virus cells. Indinavir has been used to deal with . Indinavir is not a treatment for HIV or AIDS.Indinavir may also be utilized for purposes.

Used for treatment: HIV-1 Infections

Indinavir inhibits the HIV viral protease enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

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How to use indinavir

Follow all instructions. Do not take this medicine in smaller or larger quantities or for longer than suggested. Indinavir should be taken on an empty stomach, at least 1 hour before or two hours following a meal. Indinavir is normally taken every 8 hours round the clock. Take the medicine at the exact same time daily.

Take indinavir with a Complete glass of water or skim milk. You could drink coffee, juice, or tea using this medication. Drink at least 6 glasses of water each day to avoid kidney stones when you’re taking indinavir. If you prefer to choose the medication with food, eat only a light meal, such as dry toast with jelly, or corn flakes with skim milk and sugar. Prevent eating a meal. Use indinavir to get the most benefit.

Take your prescription refilled before you run out of medicine. When using indinavir, you’ll need regular blood tests. HIV/AIDS is treated with a mix of medication. Utilize instructed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or drug schedule without your physician’s advice. Each person who has HIV or AIDS should remain under a doctor’s care. Store at room temperature away from heat and moisture.

Keep the capsules in their original container, together with the packet or spoonful of preservative.

Interactions

Indinavir interacts with several medications. Some of the interactions are mentioned below. Patients should consult their healthcare professional before combining any medications. Triazolam, alprazolam midazolam, pimozide, lovastatin, simvastatin derivatives, and amiodarone shouldn’t be combined because of the risk of serious adverse effects resulting from indinavir increasing the blood levels of these drugs with indinavir.

Indinavir increases blood concentrations of oral contraceptives, alfuzosin, stavudine, and clarithromycin. Higher blood levels may result in side effects. Indinavir decreases the blood concentration of didanosine and can reduce the effectiveness of didanosine. Therefore, when didanosine and indinavir are being used for treatment, their ingestion ought to be separated by a single hour. Indinavir may inhibit the break-down of these cholesterol-lowering drugs lovastatin, simvastatin, and atorvastatin.

This may increase the chance of muscle breakdown which may be seen when these drugs accumulate in the human body. Ketoconazole, itraconazole, delavirdine and clarithromycin can boost blood levels of indinavir and result in more frequent or severe side effects from indinavir. Rifampin, rifabutin, St. John’s Wort and efavirenz reduce the blood levels of indinavir and thus can lessen the effect of indinavir. Indinavir increases the probability of side effects such as fainting, prolonged erection, and low blood pressure and blood levels of sildenafil.

How to Pronounce Indinavir

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