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Telmisartan is an angiotensin II receptor antagonist. Telmisartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.Telmisartan is used to treat hypertension . It’s sometimes given with other blood pressure medications.Telmisartan is also used to reduce the probability of heart attack stroke, or death from heart problems in individuals that are at least 55 years older with risk factors for acute heart disorders.Telmisartan might also be used for purposes not listed in this medication guide.
Telmisartan interferes with the binding of angiotensin II into the angiotensin II AT1-receptor by binding reversibly and selectively to the receptors in vascular smooth muscle and the adrenal gland. As angiotensin II is a vasoconstrictor, which also stimulates the synthesis and release of aldosterone, blockage of its own effects contributes to decreases in systemic vascular resistance. Telmisartan doesn’t impair the angiotensin converting enzyme, other hormone receptors, or ion channels. Studies also suggest that telmisartan is a partial agonist of PPARОі, which is a recognized target for antidiabetic drugs. This implies that telmisartan can improve carbohydrate and lipid metabolism, as well as control insulin resistance without causing the side effects which are related to full PPARОі activators.
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How to use telmisartan
Follow all directions on your prescription label. Your physician may change your dose to be certain that to get the best results. Do not take this medication in smaller or larger amounts or for longer than recommended. Don’t crush, chew, or split a telmisartan tabletcomputer. Keep each tablet in its blister pack until you’re prepared to shoot it. Tear or cut on the blister besides the remainder of the package and peel the paper liner back.
Push on the tablet through the foil. It may take two to four months until your symptoms change. Continue using the medication and tell your physician if your symptoms do not improve. Your blood pressure will have to be checked. You might have blood pressure when taking telmisartan. Call your physician if you are sweating more than normal, or if you are ill with vomiting or nausea.
If you’re being treated for hypertension, keep using this medicine even in the event that you are feeling well. High blood pressure often has no signs. You might need to use blood pressure medication for the rest of your life. Store telmisartan pills in their original package away from moisture and heat.
- sinus pain and congestion (sinusitis)
- back pain
Blood concentrations of digoxin and lithium can boost . Hence blood levels of digoxin and lithium should be monitored and doses adjusted if necessary. Combining telmisartan with potassium-sparing diuretics, triamterene, amiloride), potassium supplements, or salt substitutes containing potassium may lead to hyperkalemia. Combining telmisartan or other ARBs with anti inflammatory anti inflammatory drugs or with poor kidney function may result in reduced kidney function, including kidney failure.
These effects usually are reversible. There are reports that aspirin and other NSAIDs such as ibuprofen, indomethacin, and naproxen may reduce the effects of ARBs.