Venlafaxine Hydrochloride

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Brand Names
Effexor, Effexor XR

Venlafaxine hydrochloride Information

Venlafaxine is a serotonin and norepinephrine reuptake inhibitor antidepressant. Venlafaxine affects chemicals. Venlafaxine is used to deal with major depressive disorder, stress, and panic disorder.Venlafaxine may also be used for purposes.

Used for treatment: Generalized Anxiety Disorder, Vasomotor Symptoms

The precise mechanism of action of venlafaxine is unknown, but seems to be associated with the its potentiation of neurotransmitter activity in the CNS. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), inhibit the reuptake of both serotonin and norepinephrine with a potency greater for the 5-HT than for the NE reuptake procedure. The two venlafaxine and the ODV metabolite have weak inhibitory effects on the reuptake of dopamine but, unlike the tricyclics and like SSRIs, they aren’t active at histaminergic, muscarinic, or alpha(1)-adrenergic receptors.

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How to use venlafaxine hydrochloride

Follow all directions. Do not take this medicine in bigger or smaller amounts or for longer than suggested. Try to take venlafaxine. Do not crush, chew, break, or start an extended-release capsule or pill. To make the extended-release capsule much easier to consume, you may open the capsule and sprinkle the medicine. Swallow all of the mix and do not spare any for later use.

It could take several weeks until your symptoms change. Continue using the medication as directed. Do not quit using venlafaxine without first talking to your physician. You might have side effects if you stop taking this medication. Your blood pressure will have to get checked frequently. This medicine can enable you to have a false positive drug screening evaluation. Tell the laboratory staff that you’re taking venlafaxine if you give a urine sample for drug screening.

Side Effects

  • dizziness
  • nausea
  • sleepiness
  • insomnia
  • loss of appetite
  • constipation
  • sexual side effects
  • dry mouth
  • weakness
  • sweating
  • nervousness

Interactions

Venlafaxine should not be used in combination with a monoamine oxidase inhibitor like phenelzine, tranylcypromine , isocarboxazid, and selegiline, or within 14 days of quitting the MAOI. At least 5 days should be allowed after stopping venlafaxine. Combinations of both SNRIs and MAOIs may lead to acute, sometimes fatal, reactions including body temperature, muscle rigidity, rapid fluctuations of heart rate and blood pressure and coma.

Similar reactions may occur if venlafaxine is coupled with antipsychotics, tricyclic antidepressants or other drugs that affect serotonin in the brain. Examples include tryptophan, sumatriptan , lithiumion, linezolid, tramadol, and St. John’s Wort. Because venlafaxine is associated with bleeding combining venlafaxine with other drugs which are related to bleeding, nonsteroidal anti-inflammatory drugs, warfarin or aspirin may increase the risk of bleeding. Most medications affecting the brain such as venlafaxine have the potential.

Caution is advised especially early in the course of therapy. Security hasn’t been established in children.

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